Received: 15 April 2019
Accepted: 12 June 2019
First Online: 14 August 2019
Ethics approval and consent to participate
: Informed consent was obtained from both patients’ parents to review and analyze their medical information for the purposes of this study.
: Informed consent was obtained from both patients’ parents to use this medical information in a scientific journal publication.
: Dr. Jennifer Cohen was a one-time consultant for Sobi Inc. in regards to hereditary tyrosinemia type I. Jessica Burfield has served as a paid consultant to Abbott Nutrition and Vitaflo USA and she was compensated for participation in advisory board sponsored by Nutricia. Dr. Helio Pedro is on the speaker bureau for Hypophosphatasia for Alexion. Dr. Can Ficicioglu served as an advisor or consultant for: Biomarin Genzyme, Sobi, Recordati, Orphan Tech., Shire, Cycle Pharma, Horizon, Alexion and Synlogic; he also received grants for clinical research from: Vtesse, Shire, Sangamo, Orphan Tech., and Genzyme.