Funding for this research was provided by:
Fundação para a Ciência e a Tecnologia (PTDC/SAU-ENB/112306/2009, SFRH/BD/85358/2012, COMPETE, POCI- 01-0145-FEDER-007440, UID/NEU/04539/2013, Programa Ciência 2008)
Received: 4 March 2019
Accepted: 9 October 2019
First Online: 8 November 2019
Ethics approval and consent to participate
: All study procedures involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.The study was approved by the Ethics Committee of the Faculty of Medicine, University of Coimbra, and an informed consent was signed by participants prior to study participation.
: Not applicable.
: The authors declare that they have no competing interests.