Funding for this research was provided by:
Grant of the National Natural Science Foundation of China (81700419)
Grant of CAMS Initiative for Innovative Medicine (NO.2016-I2M-1-016)
Received: 9 October 2019
Accepted: 18 December 2019
First Online: 8 January 2020
Ethics approval and consent to participate
: This study was approved by the ethics committee of the institutional review board at Fuwai Hospital (Approval No.:2017–877). All the patients and their related family members accepting the genetic testing assigned a consent form.
: The authors give their consent for publication of this manuscript.
: The authors declare that they have no competing interests.