Funding for this research was provided by:
Japan Agency for Medical Research and Development (20ek0109468, 18ek0109177, 19ek0109273)
Ministry of Education, Culture, Sports, Science and Technology
Takeda Science Foundation
Received: 15 March 2020
Accepted: 15 June 2020
First Online: 24 July 2020
Ethics approval and consent to participate
: All procedures were performed in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000.
: Written informed consent was obtained from the parents of all subjects included in the study.
: All authors declare that they have no conflict of interest.