Funding for this research was provided by:
National Natural Science Foundation of China (81571587, 81771757)
CAMS Initiative for Innovative Medicine (2017-12M-3-001)
The National Key Research and Development Program of China (2016YFC0901500)
Received: 3 July 2020
Accepted: 5 October 2020
First Online: 14 October 2020
: All patients were enrolled after written informed consent was completed. This study was approved by the ethics review committees of the Peking Union Medical College Hospital (Beijing, China, ethics approval number: No. S-442). This study was registered on Clinical Trials.gov (clinical trial registration number: NCT01670695).
: Written informed consent for publication was obtained from all participants.
: The authors declare that there is no conflict of interest regarding the publication of this paper.