Funding for this research was provided by:
Japan Society for the Promotion of Science (15K09203)
Japan Agency for Medical Research and Development (JP19ek0109268)
Ministry of Health, Labour and Welfare (H29-023)
Received: 16 November 2020
Accepted: 18 February 2021
First Online: 2 March 2021
: We obtained written informed consent from all subjects prior to prospective assignment to the cohort, data collection, and serum collection (approval number: 365). The present study was also approved by the institutional review board of the Kinki-Chuo Chest Medical Centre, Sakai City, Osaka, Japan (approval number: 576).
: All subjects of this study provided written informed consent for the publication of the present findings.
: YI is a member of the advisory board of SAVARA and steering committee of Boehringer Ingelheim regarding in this study. There are no other conflicts of interest to report.