Funding for this research was provided by:
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Hospital de Clínicas de Porto Alegre
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
Received: 10 February 2021
Accepted: 21 May 2021
First Online: 3 June 2021
: This study was approved by the HCPA Research Ethics Committee (protocol #52645116500005327) and ClinicalTrials.gov (NCT03871673). All participants or their legal guardians signed an informed consent form.
: “Not applicable”.
: TN is currently an employee of Ultragenyx Farmacêutica Brasil LTDA and hold stock in Ultragenyx Pharmaceutical Inc. All other authors declare no conflicts of interest.