Bisschoff, Michelle http://orcid.org/0000-0002-0112-0691
Smuts, Izelle http://orcid.org/0000-0002-1091-5912
Dercksen, Marli http://orcid.org/0000-0002-5152-4782
Schoonen, Maryke http://orcid.org/0000-0001-6762-2232
Vorster, Barend C. http://orcid.org/0000-0003-2371-288X
van der Watt, George http://orcid.org/0000-0002-5197-568X
Spencer, Careni http://orcid.org/0000-0001-9638-2071
Naidu, Kireshnee http://orcid.org/0009-0007-2302-4901
Henning, Franclo http://orcid.org/0000-0002-4006-8101
Meldau, Surita http://orcid.org/0000-0002-0612-2071
McFarland, Robert http://orcid.org/0000-0002-8833-2688
Taylor, Robert W.
Patel, Krutik http://orcid.org/0000-0001-6806-8675
Fassad, Mahmoud R. http://orcid.org/0000-0003-2568-8326
Vandrovcova, Jana http://orcid.org/0000-0001-9508-0477
Wanders, Ronald J. A. http://orcid.org/0000-0001-7818-1452
van der Westhuizen, Francois H. http://orcid.org/0000-0002-7879-1776
,
Funding for this research was provided by:
Medical Research Council (MR/S005021/1, MR/W019027/1)
South African Medical Research Council
National Research Foundation (PMDS22080748827, 121311)
Wellcome Trust Centre for Mitochondrial Research (203105/Z/16/Z)
Mitochondrial Disease Patient Cohort (G0800674)
Lily Foundation
NIHR Biomedical Research Centre for Ageing and Age-related Disease
North-West University
Article History
Received: 7 July 2023
Accepted: 20 December 2023
First Online: 14 January 2024
Declarations
:
: The patients in this study were enrolled as part of the ICGNMD study with ethical approval numbers 19/LO/1796 [Health Research Authority (HRA) and Health and Care Research Wales (HCRW)], NWU-00966-19-A1 and NWU-00966-19-A1-01 [Health Research Ethics Committee (NWU-HREC) of the Faculty of Health Sciences, North-West University], 296/2019 (Faculty of Health Sciences Research Ethics Committee, University of Pretoria), B19/01/002 (Health Research Ethics Committee, Stellenbosch University), and 605/2020 (Faculty of Health Sciences Human Research Ethics Committee, University of Cape Town), following informed consent/assent.
: The informed consent/assent accounts for the publication of our research data are available upon request.
: The authors declare that they have no competing interests.