Tatebe, Harutsugu
Kasai, Takashi
Ohmichi, Takuma
Kishi, Yusuke
Kakeya, Tomoshi
Waragai, Masaaki
Kondo, Masaki
Allsop, David
Tokuda, Takahiko
Funding for this research was provided by:
Japan Society for the Promotion of Science (15K09322)
Japan Agency for Medical Research and Development (16dk0207030h0001)
Article History
Received: 21 April 2017
Accepted: 18 August 2017
First Online: 4 September 2017
Competing interest
: Drs Kishi and Kakeya are employees of SCRUM Inc. Drs Tatebe, Kasai, Omichi, Waragai, Kondo, Allsop and Tokuda declare that they have no competing interests.
: All subjects including patients with DS provided written informed consent to participate in the study, which was approved by the University Ethics Committee (Kyoto Prefectural University of Medicine, Kyoto, Japan; the reference number RBMR-C-1027-2). The study procedures were designed and performed in accordance with the Declaration of Helsinki.
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