Funding for this research was provided by:
Japan Society for the Promotion of Science (17K16409, 19K08065, 19K06918, 19H05201)
Takeda Science Foundation
National Institutes of Natural Sciences (BS271002, BS291005, BS281009)
Received: 24 April 2020
Accepted: 9 June 2020
First Online: 16 June 2020
Ethics approval and consent to participate
: All experiments were carried out according to the Guide for the Care and Use of Laboratory Animals at the University of Tsukuba, and the National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. 8023, revised 1978). All efforts were made to minimize animal suffering and the number of animals used.
: Not applicable.
: The authors declare that they have no competing interests.