Funding for this research was provided by:
Japan Society for the Promotion of Science (19K22477)
Japan Agency for Medical Research and Development (20gm0910012)
Received: 18 July 2020
Accepted: 9 October 2020
First Online: 15 October 2020
Ethics approval and consent to participate
: All experiments were conducted with the approval of the Hokkaido University Institutional Animal Care and Use Committee. All efforts were made to minimize the number and suffering of animals used in the experiments.
: Not applicable.
: The authors declare that they have no competing interests.