Funding for this research was provided by:
Japan Society for the Promotion of Science (17H05550, 19K06881, 26290002, 16H06276, 15H05872)
Takeda Science Foundation
Received: 15 September 2020
Accepted: 7 December 2020
First Online: 7 January 2021
Ethics approval and consent to participate
: This study was performed in accordance with the Guidelines for Animal Experimentation at Gunma University Graduate School of Medicine and was approved by the Gunma University Ethics Committee (Permit Number: 14-006 and 19-009). Every effort was made to minimize the number of animals used and their suffering.
: Not applicable.
: The authors declare that they have no conflicts of interest with the contents of this manuscript.