Funding for this research was provided by:
Ministry of Education, Culture, Sports, Science and Technology
JST CREST (JPMJCR1655)
Japan Society for the Promotion of Science (16K18359, 15F15408, 26115502, 25116530, JP16H06280, 19F19310, 20H03552)
Shimadzu Science Foundation
Takeda Science Foundation
Kanae Foundation for the Promotion of Medical Science
Research foundation for Opto-Science and Technology
Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care
Kato Memorial Bioscience Foundation
Japan Foundation for Applied Enzymology
SENSHIN Medical Research Foundation
Life Science Foundation of Japan
The Uehara Memorial Foundation
Brain Science Foundation
Kowa Life Science Foundation
Received: 28 June 2020
Accepted: 8 January 2021
First Online: 10 February 2021
Ethics approval and consent to participate
: All experiments were performed in accordance with the Science Council of Japan’s Guidelines for Proper Conduct of Animal Experiments. Experimental protocols were approved by the Institutional Animal Care and Use Committee at the University of Tsukuba.
: Not applicable.
: The authors declare that they have no competing interests.