Funding for this research was provided by:
National Key R&D Program of China (2018YFC1312100)
Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences (2016-I2M-1-001, 2019-I2M-1-003, 2017-I2M-4-002)
Received: 2 September 2021
Accepted: 17 September 2021
First Online: 12 October 2021
: All patients provided written informed consent, and the study was approved by the Ethics Committee of National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (Approval Number: 17-093/1349).
: Not applicable.
: Yuchen Jiao, Dongbing Zhao, Pei Wang, Qianqian Song and Pinli Yue have filed patents/patent applications based on the technology and data generated from this work. Yuchen Jiao is one of the cofounders, has owner interest in Genetron Holdings, and receives royalties from Genetron. The remaining authors disclose no conflicts.