Funding for this research was provided by:
Natural Science Foundation of Beijing Municipality (7172134 and 7192128)
National Natural Science Foundation of China (8197268)
PUMC Youth Fund and Fundamental Research Funds for the Central Universities (3332015113 and 2017350002)
National Science and Technology Major Projects for Major New Drugs Innovation and Development (2019ZX09301170)
CMAS Innovation Fund for Medical Sciences (2021-I2M-1-026)
Received: 18 April 2022
Accepted: 23 April 2022
First Online: 3 June 2022
: All the animal experiments were approved by the Institutional Animal Care and Use Committee of the Chinese Academy of Medical Science and were conducted in accordance with the recommendations of “Regulations of experimental animals.”
: Not applicable.
: The authors declare that they have no competing interests.