Received: 9 August 2022
Accepted: 22 October 2022
First Online: 15 November 2022
: Blood samples were obtained from CLL patients at The Ohio State University, who consented to an Institutional Review Board–approved tissue procurement protocol or who were enrolled in Institutional Review Board–approved clinical trial of nemtabrutinib in CLL. All patients gave written informed consent in accordance with the Declaration of Helsinki. All animal protocols were reviewed and approved by The Ohio State University Institutional Animal Care and Use Committee.
: Not applicable.
: The data that support the findings of this study are available on request from the corresponding author.
: JCB reports consulting, stock ownership with Vincerx, consulting with AstraZeneca, Syndax, Janssen, Pharmacyclics, Acerta, and Trillium that are outside of the submitted work. JAW has consulted for Abbvie, AstraZeneca, Beigene, Genentech, Janssen, Loxo, Newave, Pharmacyclics, and Schrodinger and receives research funding from Abbvie, Janssen, Morphosys, and Schrodinger. KAR receives research funding from Genentech, AbbVie, Novartis, and Janssen, consults for AstraZeneca, Beigene, Genentech, AbbVie, Pharmacyclics, and Innate Pharma and received travel funding from AstraZeneca. DS has received honoraria from Newave.