Funding for this research was provided by:
National Natural Science Foundation of China (No. 81372327, No. 81572427, No. 81202300, No. 81502530, No.31671348)
Received: 21 July 2018
Accepted: 14 December 2018
First Online: 3 January 2019
: All of the animal studies met the National Institutes of Health guidelines and were approved by the Committee on the Ethics of Animal Experiments of the Tongji Medical College, HUST.
: We have obtained consents to publish this paper from all the participants of this study.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.