Funding for this research was provided by:
National Natural Science Foundation of China (81573445)
Natural Science Foundation of Beijing Municipality (7182115)
Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study (BZ0150)
CAMS Innovation Fund for Medical Science (2017-I2M-3-011, 2017-I2M-3-010)
The Drug Innovation Major Project of China (2018ZX09711001-003-001)
Received: 22 November 2018
Accepted: 27 January 2019
First Online: 4 February 2019
Ethics approval and consent to participate
: All experiments were approved by the Experimental Animal Welfare and Ethics Committee of the Institute of Materia Medica, Chinese Academy of medical Sciences (No. 001004). And a written informed consent was obtained from all patients.
: All contributing authors agree to the publication of this article.
: The authors declare that they have no competing interests.
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