Funding for this research was provided by:
Natural Science Foundation of Shandong Province of China (2017CXGC1203, ZR2019BH057)
National Natural Science Foundation of China (81571284, 81702468, 81874083, 81802966)
National Natural Science Foundation of China (81902540)
Natural Science Foundation of Shandong Province of China (2017G006012)
Taishan Scholars of Shandong Province of China (No. ts201511093)
Received: 31 October 2019
Accepted: 25 February 2020
First Online: 6 April 2020
Ethics approval and consent to participate
: All experimental protocols were approved by the Ethics Committee of the Qilu Hospital (Jinan, China) and performed in accordance with the relevant guidelines and regulations. Written informed consent was obtained from all patients. All animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of Shandong University (Jinan, China).
: Not applicable.
: The authors declare that they have no competing interests.