Funding for this research was provided by:
BC Children's Hospital Research Institute
Michael Cuccione Foundation
BC Proteomics Network
Canada Research Chairs
Michael Smith Foundation for Health Research
BC Children’s Hospital Foundation
Received: 7 September 2020
Accepted: 10 January 2021
First Online: 15 March 2021
Ethics approval and consent to participate
: Patient sample samples were collected with informed consent and experiments were performed as approved by the University of British Columbia Children & Women’s Research Ethics, and conformed with standards defined in the WMA Department of Helsinki and the Department of Health and Human Services Belmont Report. Patient clinical information were de-identified prior to sample retrieval.Primary ALL cells engraftment in mice was performed in accordance with an Institutional Animal Care and Use Committee-approved protocol (A15–0187).
: Not applicable.
: The authors declare no conflicting interests.