Funding for this research was provided by:
Ministero della Salute (ER-2015-2360441-Eranet)
Associazione Italiana per la Ricerca sul Cancro (IG18474, IG24397)
European Regional Development Fund (ODD4PEGASEMP)
Fundação para a Ciência e a Tecnologia (ENMed/0005/2015)
Received: 24 February 2021
Accepted: 24 May 2021
First Online: 2 June 2021
: The in vivo studies and the collection and manipulation of human samples were approved by the Italian Ministry of Health and by the competent Ethics Committee, as reported in the Methods section.
: All the authors have read and approved the submission of the current version of the manuscript.
: V. M. and N. A. F. were former employees of Treat U, SA. V. M. and J. N.M. are share-holders of TREAT U, SA. The remaining authors declare no competing interests.