Funding for this research was provided by:
National Natural Science Foundation of China (82173250)
Fujian Natural Science Foundation (2021J01365, 2020J011097)
Education and Scientific Research Foundation of Fujian Province (2060402)
Fujian Provincial Health and Family Planning Research Medical Innovation Project (2019-cx-3)
Joint Funds for the innovation of science and technology, Fujian Province (2018Y9098)
Fujian Medical Innovation Project (2020CXA001)
Received: 26 January 2022
Accepted: 25 March 2022
First Online: 23 April 2022
: All participants provided informed written consent. This study was approved by the Human Research Ethics Committees of the Fujian Medical University and was carried out following the principles embodied in the Declaration of Helsinki. All in vivo animal experiments were approved by the Committee on the Ethics of Animal Experiments of Fujian Medical University.
: All authors have given their consent for publication.
: Zhi-Wen Chen, Jian-Fei Hu, Zu-Wei Wang contributed equally to this work and all should be considered co-first authors. Shi Chen, Yi-Feng Tian, Long Huang, also contributed equally, and all should be considered the co-corresponding author. The authors declare that they have no competing interests.