Funding for this research was provided by:
National Natural Science Foundation of China (82073344, 81874217, 81672983)
General Project of Huai’an Health Scientific Research (HAWJ202030)
the Jiangsu Provincial Health and Health Commission Scientific Research Project (Z2021036)
Received: 22 April 2022
Accepted: 20 August 2022
First Online: 26 August 2022
: The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Ethics Committee and Institutional Review Board of the First Affiliated Hospital of Nanjing Medical University. All samples were collected with patient consent and were approved by the institutional review board of Nanjing Medical University. Animal experiments were approved by the Institutional Animal Care and Use Committee of Nanjing Medical University (IACUC-2104040).
: All the patients involved in our study obtained written consent for publication.
: The authors declare that they have no competing interests.