Funding for this research was provided by:
Chinese Academy of Medical Sciences Initiative for Innovative Medicine (CAMS-2017-I2M-1-002)
Text and Data Mining valid from 2019-09-10
Received: 1 February 2019
Accepted: 4 September 2019
First Online: 10 September 2019
Ethics approval and consent to participate
: This study was approved by the Institutional Review Board of Peking Union Medical College Hospital (Registration No. ZS-1245 and HS-1474 for genetic tests and risk-reducing surgeries, respectively). The Chinese Human Genetic Resources Management Office of the National Ministry of Science and Technology approved this study (registration No. 1901, ExternalRef removed). All family members provided informed consent.
: Written consent to publish this information was obtained from the study participants.
: The authors declare that they have no competing interests.