Funding for this research was provided by:
Programme Hospitalier de la Recherche Clinique
Research Grant from the Société Française d’Anesthésie – Réanimation
Received: 20 November 2017
Accepted: 9 January 2018
First Online: 29 January 2018
: Cyril Touchard works as a resident in the Saint Louis Lariboisière University Hospitals. Alexa Hollinger works as a postdoctoral research fellow at the Saint Louis Lariboisière University Hospitals. The other authors are members of the steering committee and/or investigators in the FROG-ICU study.
: The study was conducted in France and Belgium in accordance with Good Clinical Practice (Declaration of Helsinki 2002) and Ethical Committee approvals (Comité de Protection des Personnes—Ile de France IV, IRB number 00003835 and Commission d’éthique biomédicale hospitalo-facultaire de l’hôpital de Louvain, IRB number B403201213352). It is registered on ClinicalTrials.gov (NCT01367093). Patients were included from August 2011 to June 2013.
: Not applicable.
: Etienne Gayat received a research grant from sphingotec, consultancy fees from Magnisense, Roche Diagnostics. Alexandre Mebazaa received speaker’s honoraria from Abbott, Novartis, Orion, Roche et Servier and a fee as a member of the advisory board and/or Steering Committee from Cardiorentis, Adrenomed, MyCartis, Neurotronik, and sphingotec. All other co-authors have no conflicts of interest related to the present manuscript.
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