Funding for this research was provided by:
Danone Research Centre for Specialised Nutrition
Received: 16 March 2018
Accepted: 17 May 2018
First Online: 12 June 2018
Ethics approval and consent to participate
: The study was conducted in the Netherlands, Belgium, and France in accordance with good clinical practice and ethics committee approvals (METC Isala, Zwolle, the Netherlands [METC number 14.12178/NL51412.075.14], Commissie voor medische ethiek, Gent, Belgium [B670201525143], and Comité de protection des personnes sud-ouest et outré mer III, Bordeaux, France [2015-A00186-43]). Written informed consent was obtained from the patients or their legal representatives.
: AvZ reported that he has received honoraria for advisory board meetings, lectures, and travel expenses from Abbott, Baxter, B. Braun, Danone-Nutricia, Fresenius Kabi, Lyric, and Nestlé-Novartis. Inclusion fees for patients in the Protill trial from Nutricia were paid to the local ICU research foundation. JDW has been a consultant for Bayer Healthcare, MSD, and Pfizer. JdW, PvH, MK, and ZH are employees of Nutricia Research. LP and HK declare that they have no competing interests.
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