Received: 22 August 2018
Accepted: 24 September 2018
First Online: 28 October 2018
Ethics approval and consent to participate
: The ATHOS-3 protocol was approved by a research ethics board at each participating institution. The study was conducted in accordance with Good Clinical Practice guidelines, applicable local regulations, and the ethical principles described in the Declaration of Helsinki. Written informed consent was obtained from all patients or their legal surrogates.
: Not applicable.
: LC, SC, and GT are employees and shareholders of La Jolla Pharmaceutical Company.
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