Text and Data Mining valid from 2019-09-18
Received: 16 June 2019
Accepted: 28 August 2019
First Online: 18 September 2019
Ethics approval and consent to participate
: All patients, their relatives or legal representatives gave their informed consent for the admission to the ICU and to undergo specific interventions. Patients were not re-contacted for the purpose of this study. To re-contact patients for informed consent for the current retrospective chart study would introduce a serious bias because a large proportion is out of follow-up or deceased. All procedures were carried out per standard of care per protocol. This retrospective cohort study was performed in accordance with the protocol, the principles of the Declaration of Helsinki 1964 as modified by the 64th WMA General Assembly, Fortaleza, Brazil, October 2013, with notes of clarification on paragraph 29 and 30 added by the WMA General Assembly, and the local national laws governing the conduct of clinical research studies. The study was approved by the ethics committee of the Maasstad Hospital Rotterdam, the Netherlands (MZ0582-07-14, L2017-030).
: Not applicable.
: WPB, MK and SD declare that they have no competing interests. CI has received a grant from CytoSorb to commence a randomized controlled trial on the effect of the adsorber on the microcirculation of critically ill patients at the department of Intensive Care of the Erasmus Medical Center Rotterdam.