Received: 24 July 2019
Accepted: 9 October 2019
First Online: 12 November 2019
: All animals were treated in accordance with the NIH guidelines for animal care. Experiments were performed with approval of the Local Animal Care and Use Committee (North Rhine-Westphalia State Agency for Nature, Environment and Consumer Protection, Recklinghausen, Germany; ref. 84-02.04.2012.A152). The authors ensure that their research complies with the commonly accepted “3Rs”: replacement, reduction, and refinement.
: The authors declare that they have no competing interests.