Funding for this research was provided by:
National Institutes of Health (R01GM117622, K23GM138984, T32HL007820, R01HL126811)
Defense Advanced Research Projects Agency (FA8750-17-2-0130)
Received: 18 July 2020
Accepted: 9 November 2020
First Online: 25 November 2020
Ethics approval and consent to participate
: The clinical data used for this research was obtained from publicly available deidentified database, Medical Information Mart for Intensive Care (MIMIC-III), and does not require a separate ethics approval or consent obtaining process. The Institutional Review Board at the University of Pittsburgh Medical Center waived the review of the research plan as the data was obtained from a publicly available database with no potential violation or infringement of the ethical regulations.
: Not applicable.
: Dr. Pinsky is the inventor of a University of Pittsburgh-owned US Patent No. 10,631,792 “System and method of determining susceptibility to cardiorespiratory insufficiency” that directly applies these approaches to hypotension prediction. The other authors have no competing financial or non-financial interests for current work.