Funding for this research was provided by:
Keenan Chair in Critical Care
Received: 29 September 2020
Accepted: 11 December 2020
First Online: 11 January 2021
Ethics approval and consent to participate
: Approved by the Ethics Committee of St. Michael’s Hospital (REB #15-073) and registered on ClinicalTrials.gov (NCT02434016).
: Not applicable.
: Laurent Brochard has indicated the following financial relationship: “LB's laboratory received research grants and/or equipment from Medtronic Covidien, Fisher Paykel, Philips, Sentec, Air Liquide and General Electric outside the scope of this study.” Irene Telias has indicated the following: "MBMed SA Argentina," "Covidien, Argentina," and "Canadian Institutes of Health Research". Ewan C. Goligher has indicated the following: "Getinge" and "Timpel". Ricard M. Artigas has indicated the following: "Medtronic". Leo Heunks has indicated the following: "Ventfree, USA" and "Getinge, Sweden". Christer Sinderby has indicated the following: Dr. Sinderby has made inventions related to neural control of mechanical ventilation that are patented. The patents are assigned to the academic institution(s) where inventions were made. The license for these patents belongs to Maquet Critical Care. Future commercial uses of this technology may provide financial benefit to Dr. Sinderby through royalties. Dr Sinderby owns 50% of Neurovent Research Inc (NVR). NVR is a research and development company that builds the equipment and catheters for research studies. NVR has a consulting agreement with Maquet Critical Care, which is a subsidiary of Getinge. Supported by the RS McLaughlin Foundation.