Funding for this research was provided by:
Deutsche Zentrum für Lungenforschung
Deutsche Forschungsgemeinschaft (DA 1209/4-3, ME 3696/3-1)
Medizinische Hochschule Hannover (MHH)
Received: 2 September 2020
Accepted: 10 February 2021
First Online: 22 February 2021
Ethics approval and consent to participate
: Human umbilical vein endothelial cells (HUVECs) were isolated from human umbilical veins (donor approval, Hannover Medical School Nr. 1303-2012). All mouse experiments were approved by the local authorities at Hannover Medical School and conducted in accordance with institutional and governmental guidelines (LAVES Lower Saxony, Ref. No. 18/2817). The Mount Desert Island Biological Laboratory (Bar Harbor, ME) animal care committee approved the animal protocol for the zebrafish experiments (IACUC protocol #1703). The postmortem biopsies were waived by the Medical Ethical Committee of the UMCG, Groningen, The Netherlands (METc 2011/372) [CitationRef removed]. The collection of the BALf and serum samples was approved according to the ethics committee of Hannover Medical School (MHH, EK 8146_BO_K_2018).
: Not applicable.
: SD, VE, TOI, HS, BS, AP, KT, TP, JMD, MVM, AG, RG, KS, SMP, HH declare no conflict of interest. TT is founder and shareholder of Cardior Pharmaceuticals GmbH.