Richter, Sophie
Winzeck, Stefan
Czeiter, Endre
Amrein, Krisztina
Kornaropoulos, Evgenios N.
Verheyden, Jan
Sugar, Gabriela
Yang, Zhihui
Wang, Kevin
Maas, Andrew I. R.
Steyerberg, Ewout
Büki, András
Newcombe, Virginia F. J.
Menon, David K.
,
Amrein, Krisztina
Andelic, Nada
Andreassen, Lasse
Anke, Audny
Azouvi, Philippe
Bellander, Bo‑Michael
Benali, Habib
Buki, Andras
Caccioppola, Alessio
Calappi, Emiliana
Carbonara, Marco
Citerio, Giuseppe
Clusmann, Hans
Coburn, Mark
Coles, Jonathan
Correia, Marta
Czeiter, Endre
De Keyser, Véronique
Degos, Vincent
Depreitere, Bart
Eikenes, Live
Ezer, Erzsébet
Foks, Kelly
Frisvold, Shirin
Galanaud, Damien
Ghuysen, Alexandre
Glocker, Ben
Haberg, Asta
Haitsma, Iain
Helseth, Eirik
Hutchinson, Peter J.
Kornaropoulos, Evgenios
Kovács, Noémi
Kowark, Ana
Laureys, Steven
Ledoux, Didier
Lingsma, Hester
Maas, Andrew I. R.
Manley, Geoffrey
Menon, David K.
Menovsky, Tomas
Misset, Benoit
Muraleedharan, Visakh
Nakken, Ingeborg
Newcombe, Virginia
Nordhøy, Wibeke
Nyirádi, József
Ortolano, Fabrizio
Parizel, Paul M.
Perlbarg, Vincent
Persona, Paolo
Peul, Wilco
Posti, Jussi P.
Puybasset, Louis
Richter, Sophie
Roe, Cecilie
Roise, Olav
Rossaint, Rolf
Rossi, Sandra
Rueckert, Daniel
Skandsen, Toril
Sorinola, Abayomi
Stamatakis, Emmanuel
Steyerberg, Ewout W.
Stocchetti, Nino
Takala, Riikka
Tamás, Viktória
Tenovuo, Olli
Vámos, Zoltán
Van der Steen, Gregory
Van Hecke, Wim
Vyvere, Thijs Vande
Verheyden, Jan
Vik, Anne
Volovici, Victor
Westlye, Lars T.
Williams, Guy
Winzeck, Stefan
Ylén, Peter
Zoerle, Tommaso
Funding for this research was provided by:
Wellcome Trust (222213/Z/20/Z)
Academy of Medical Sciences
the Health Foundation
Article History
Received: 20 September 2022
Accepted: 19 November 2022
First Online: 29 November 2022
Declarations
:
: Ethical approval for CENTER-TBI was obtained in accordance with all relevant laws and regulations for each recruiting site. Details may be found at: . Informed consent from the patient or legal representative/next of kin was obtained for all participants. Whilst the patient was comatose assent was given by a proxy (next of kin) and consent sought when the patient regained capacity.
: Not applicable.
: DKM received personal fees from Lantmannen AB, GlaxoSmithKline plc, Calico Life Sciences LLC, Integra Neurosciences, and NeuroTrauma Sciences, LLC; and grants from GlaxoSmithKline plc and Lantmannen AB, outside the presented work. VFJN holds a grant from Roche Pharmaceuticals paid to the institution for an analysis outside the presented work. KW reports stock options with Gryphon Bio. AIRM declares personal fees from NeuroTrauma Sciences and Novartis and participated in the DSMB of PresSura Neuro during the conduct of the study.