Funding for this research was provided by:
National Cancer Institute (R01CA104670, 5K017CA218166-02)
National Institutes of Health (U01HL37975, U01HL37948, U01HL37954, U01HL37962, U0137966, U01HL37947, P30CA134274, U01-HL38110)
Text and Data Mining valid from 2019-11-14
Received: 10 January 2019
Accepted: 15 October 2019
First Online: 14 November 2019
Ethics approval and consent to participate
: An NHLBI-appointed independent data and safety monitoring committee monitored the original DISC trial. Institutional review boards at all participating clinical centers and the data coordinating center approved both the DISC and the DISC06 Follow-Up Study protocols. The DISC06 Follow-Up Study protocol also was approved by the Fox Chase Cancer Center’s Institutional Review Board.Prior to randomization, parents/guardians provided informed consent and DISC participants provided assent, while participants provided informed consent prior to the DISC06 follow-up visit.
: Not applicable
: The authors declare that they have no competing interests.