Funding for this research was provided by:
Received: 6 November 2019
Accepted: 26 February 2020
First Online: 12 March 2020
Ethics approval and consent to participate
: The PALOMA studies were approved by an institutional review board or an equivalent independent ethics committee at each participating site. All patients provided written informed consent before study enrollment.
: Not applicable.
: JE received consulting fees from Eli Lilly, Novartis, Pfizer, Roche, and Eisai; performed contracted research for Celgene; and received honoraria and travel support from Celgene, Eli Lilly, Novartis, Pfizer, Roche, and TEVA.S-AI has advisory roles with AstraZeneca, Amgen, Hanmi Corp, Roche, Pfizer, and Novartis and has received grants from AstraZeneca and Pfizer.NM reports honoraria from Chugai, AstraZeneca, Pfizer, and Takeda and research funds from Chugai, AstraZeneca, Kyowa-Kirin, MSD, Novartis, Pfizer, Eli Lilly, and Daiichi-Sankyo.MCo reports a consulting or advisory role for Pfizer, OBI Pharma, AstraZeneca, Novartis, Pierre Fabre, Puma, and Celldex.MCr reports personal fees from Pfizer, Novartis, and Merus.HSR’s institution received research funding from Plexxikon, Macrogenics, OBI Pharma, Eisai, Pfizer, Novartis, Eli Lilly, Roche, and Merck.RSF received consulting fees from Pfizer, Bayer, Novartis, Bristol-Myers Squibb, and Merck as well as other research funding from Pfizer and honoraria from Bayer, Pfizer, Bristol-Myers Squibb, Novartis, Eisai, and Eli Lilly.PS, EB, and DRL are employees of and own stock in Pfizer.JR declares that there are no competing interests.