Funding for this research was provided by:
Radius Health, Inc.
Received: 31 March 2020
Accepted: 13 August 2020
First Online: 11 September 2020
Ethics approval and consent to participate
: The study protocol and relevant supporting information were approved by the institutional review board at each participating site or by a national central review board. The trial was performed in accordance with ethical principles consistent with the Declaration of Helsinki and International Council of Harmonisation/Good Clinical Practice and applicable regulatory requirements. Each trial participant provided written informed consent.
: Not applicable.
: AJ: No competing interest.EdV: Institutional financial support for advisory role from Daiichi Sankyo, Merck, NSABP, Pfizer, Sanofi, and Synthon and institutional financial support for clinical trials or contracted research from Amgen, AstraZeneca, Bayer, Chugai Pharma, CytomX Therapeutics, G1 Therapeutics, Genentech, Nordic Nanovector, Radius Health, Regeneron, Roche, Servier, and Synthon.CWMdHvO: Institutional financial support for clinical trials or contracted research from BMS, Boeringher Ingelheim, Crystal Therapeutics, CytomX Therapeutics, G1 Therapeutics, Pfizer, Takeda, and Synthon.PN: No competing interest.CMV: No competing interest.AWJMG: No competing interest.PA: Honoraria/advisory fees from Novartis, Roche, Macrogenics, G1 Therapeutics, Servier, Synthon, Amcure, Amgen, and Boehringer Ingleheim and travel grants from MSD, Pfizer, and Roche.YW, RGB, and MGC are employees and stockholders of Radius Health, Inc.