Funding for this research was provided by:
Florida Department of Health (8AZ10, 9AZ08, 6AZ06)
Center for Individualized Medicine, Mayo Clinic
Pharmaceutical Research and Manufacturers of America Foundation (RSGTMT17)
U.S. Department of Defense (AL130125)
Association for Frontotemporal Degeneration
National Institute of Neurological Disorders and Stroke (NS094137, NS084528, NS088689, NS097273, NS097261, NS099114, NS093865, NS084974)
Robert Packard Center for ALS Research, Johns Hopkins University
Muscular Dystrophy Association
Amyotrophic Lateral Sclerosis Association
National Institute on Aging (AG049992, AG047327)
Mayo Clinic Foundation
Mayo Clinic Gerstner Family Career Development Award
Received: 21 December 2018
Accepted: 6 May 2019
First Online: 20 May 2019
Ethics approval and consent to participate
: The Mayo Clinic Institutional Review Board (IRB) approved all procedures for this study, and we followed all appropriate protocols. All participants included in this study provided written informed consent, and all experimental methods comply with the Helsinki Declaration.
: All participants were properly consented for this study.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.