Funding for this research was provided by:
National Institutes of Health (1U2CCA233285-01, 5R01-HG006137-07, 1P01CA210944-01)
Received: 16 September 2019
Accepted: 16 December 2019
First Online: 14 January 2020
Ethics approval and consent to participate
: All animal experiments were performed according to protocols approved by the Institutional Animal Care and Use Committee of the University of Pennsylvania, (IACUC#804835).
: Not applicable.
: The authors declare that they have no competing interests.