Funding for this research was provided by:
Wellcome Trust (WT108749/Z/15/Z, WT202878/Z/16/Z, WT202878/B/16/Z)
European Research Council (615584, 788937)
Cancer Research UK (20412)
European Molecular Biology Laboratory
Received: 9 June 2020
Accepted: 4 January 2021
First Online: 18 February 2021
: The investigation was approved by the Animal Welfare and Ethics Review Board, under reference number NRWF-DO-02v2, following the Cancer Research UK Cambridge Institute guidelines on use of animals in experimental studies.
: P.F. is a member of the Scientific Advisory Boards of Fabric Genomics, Inc. and Eagle Genomics, Ltd. All other authors declare no competing interests.