Merzbacher, Charlotte http://orcid.org/0009-0000-2853-1864
Ryan, Barry http://orcid.org/0009-0006-2779-5722
Goldsborough, Thibaut http://orcid.org/0009-0007-9349-4693
Hillary, Robert F.
Campbell, Archie
Murphy, Lee
McIntosh, Andrew M.
Liewald, David
Harris, Sarah E.
McRae, Allan F.
Cox, Simon R.
Cannings, Timothy I.
Vallejos, Catalina A. http://orcid.org/0000-0003-3638-1960
McCartney, Daniel L. http://orcid.org/0000-0003-3242-0360
Marioni, Riccardo E. http://orcid.org/0000-0003-4430-4260
Funding for this research was provided by:
Wellcome Trust (104036/Z/14/Z, 216767/Z/19/Z)
Chief Scientist Office, Scottish Government Health and Social Care Directorate (CZD/16/6, CZB/4/505, ETM/55)
Scottish Funding Council (HR03006)
Biotechnology and Biological Sciences Research Council (SR176, BB/W008793/1)
UK Research and Innovation (R42550)
Engineering and Physical Sciences Research Council (EP/S02431X/1)
Article History
Received: 17 March 2023
Accepted: 20 November 2023
First Online: 5 December 2023
Declarations
:
: All components of GS received ethical approval from the NHS Tayside Committee on Medical Research Ethics (REC Reference Number: 05/S1401/89). GS has also been granted Research Tissue Bank status by the East of Scotland Research Ethics Service (REC Reference Number: 20-ES-0021), providing generic ethical approval for a wide range of uses within medical research.Ethical permission for the LBC1936 was obtained from the Multi-Centre Research Ethics Committee for Scotland (MREC/01/0/56) and the Lothian Research Ethics Committee (LREC/2003/2/29). Written informed consent was obtained from all participants.All experimental methods were in accordance with the Helsinki declaration.
: REM is a scientific advisor to the Epigenetic Clock Development Foundation and Optima Partners. DLM is a part-time employee of Optima Partners. RFH is a scientific advisor to Optima Partners. LM has received payment from Illumina for presentations and consultancy.