Zhang, Naixin
Chen, Qiaochu
Zhang, Peipei
Zhou, Kejun
Liu, Yaqing
Wang, Haiyan
Duan, Shumeng
Xie, Yongming
Yu, Wenxiang
Kong, Ziqing
Ren, Luyao
Hou, Wanwan
Yang, Jingcheng
Gong, Xiaoyun
Dong, Lianhua
Fang, Xiang
Shi, Leming
Yu, Ying
Zheng, Yuanting http://orcid.org/0000-0003-4480-8303
Funding for this research was provided by:
National Key R&D Project of China (2018YFE0201603)
National Key R&D Project of China (2022YFF0608404, 2022FY101203)
National Natural Science Foundation of China (31720103909, 32170657)
Shanghai Municipal Science and Technology Major Project (2017SHZDZX01)
State Key Laboratory of Genetic Engineering (SKLGE-2117)
111 Project (B13016)
Article History
Received: 8 November 2022
Accepted: 9 January 2024
First Online: 24 January 2024
Declarations
:
: The study was approved by the Institutional Review Board (IRB) of the School of Life Sciences at Fudan University (BE2050), and it met the requirements of the 1975 Declaration of Helsinki. Written informed consent to participate in multiomics research and allow the collection of biospecimens was approved by the IRB and obtained from the Quartet family, which includes monozygotic twin daughters (D5 and D6) and their parents (father F7 and mother M8) in Taizhou, Jiangsu Province, China.
: Not applicable.
: K.Z. is an employee of Human Metabolomics Institute, Inc. Y.X. is an employee of Shanghai Applied Protein·Technology Co. Ltd. W.Y. is an employee of Novogene Bioinformatics·Institute. Z.K. is an employee of Calibra Diagnostics. All other authors declare no competing interests.