Received: 12 March 2019
Accepted: 18 July 2019
First Online: 9 August 2019
Ethics approval and consent to participate
: This study complies with the Helsinki guidelines for human research and has been approved by the ethics committee of the University Hospital Virgen Macarena - Virgen del Rocío. The identification of each individual will remain concealed based on the ethical principles of confidentiality and privacy. All participants will receive an informed consent form with information about all treatments and the randomization process that they will approve for participation in the study. Patients assigned to the control group will receive treatment 1 or 2 after completing the study.
: Not applicable.
: The authors declare that they have no competing interests.