Funding for this research was provided by:
Lotte and John Hecht Memorial Foundation (4318)
Received: 21 August 2019
Accepted: 22 October 2019
First Online: 8 January 2020
Ethics approval and consent to participate
: This trial protocol has been approved by the Comité d’éthique de la recherche du Centre intégré universitaire de santé et de services sociaux de l’Estrie – Centre hospitalier universitaire de Sherbrooke (reference MP-31-2019-2945).Informed consent will be obtained as follows. Local research personnel will approach eligible patients directly if they are able to consent. If the eligible patient is not capable, research personnel will approach the SDM to obtain consent in person, or by telephone if the SDM is unavailable. Alternatively, the patient will be randomized and consent will be obtained subsequently under a deferred consent model, where permitted by the site REB and as per individual country requirements concerning informed consent in medical research.All personal health information collected during the study will remain strictly confidential in a secure database. Participants will be identified by an alphanumeric code, and the linkage from the alphanumeric code to identifying information will be kept in secure storage under the supervision of the local principal investigator.
: Not applicable.
: The authors declare that they have no competing interests.