Funding for this research was provided by:
Health Research Council of New Zealand (13/213)
Received: 8 September 2019
Accepted: 29 December 2019
First Online: 1 February 2020
Ethics approval and consent to participate
: The CURE RCT clinical protocol and data usage has been granted by the New Zealand South Regional Ethics Committee (reference number 14/STH/132). The CURE RCT is registered in the Australian New Zealand Clinical Trial Registry (ACTRN12614001069640). The trial was registered on 22 September 2014 (ExternalRef removed).The CURE RCT will recruit patients once family consent is obtained. However, if the treating clinician firmly believes a recruitment manoeuvre is in the best interests of the patient, and no family is available for consent, the participant will be enrolled and randomised and the appropriate protocolised recruitment manoeuvre will follow. In this case, delayed consent is obtained as early as possible. Once the participant recovers from their condition and is discharged from the ICU, we will seek their informed consent.
: Not applicable.
: The authors declare that they have no competing interests.