Funding for this research was provided by:
National Natural Science Foundation of China (81674018)
Received: 13 November 2019
Accepted: 11 June 2020
First Online: 19 June 2020
Ethics approval and consent to participate
: Central ethical approval has been confirmed from Health Authorities and Ethics Committees of the Affiliated Hospital of Shandong University of TCM (ref approval no. SDTCM20191015011). Patient recruitment will only begin upon receiving local ethical approvals from the centers. Each participant will receive detailed explanations of the trial, and written informed consent will be obtained from each participant (Additional file InternalRef removed). This trial protocol is in accordance with the principles of the Declaration of Helsinki and the Guidelines for Good Clinical Practice of the International Conference on Harmonisation.
: Not applicable.
: The authors declare that they have no competing interests.