Funding for this research was provided by:
National Research Council Canada (NRC IRAP #947684)
The Thistledown Foundation
The GeoSentinel Foundation
The Slaight Family Foundation
University Health Network Foundation
Received: 29 June 2020
Accepted: 2 July 2020
First Online: 14 July 2020
Ethics approval and consent to participate
: Ethical approval was granted by Clinical Trials Ontario (CTO) (Project ID: 2132). Initial approval was granted 8 April 2020. The Board of Record is the University Health Network (UHN) Research Ethics Board (REB). The public listing of the study can be found here: ExternalRef removed The HEROS trial received ethical approval from an appropriate ethical committee as described above. This study will be conducted in accordance with the ICH-GCP Guidelines and the principles in the Declaration of Helsinki. Potential participants are invited to view an online information video outlining the risks, benefits and procedures of the trial, and then will be invited to provide written informed consent prior to being enrolled.
: Not applicable.
: The authors declare that they do not have any competing interests.