Received: 27 September 2019
Accepted: 18 January 2020
First Online: 19 March 2020
Ethics approval and consent to participate
: Ethical approval has been obtained from Peking University People’s Hospital, and the study protocol follows the principles described in the Declaration of Helsinki for research involving human subjects. Informed consent will be obtained from all participants and their parents/guardians prior to their inclusion in the study. The children and their parents/guardians should both sign the informed consent form. The children sign the signature at “Signature of the subject,” and their parents/guardians sign the signature at “Legal guardian signature.” In addition, the parents/guardians should write down their relationship at the “Relationship with the subject” in the informed consent form. In each procedure during the clinical trial, all of the participants and their parents/guardians should be involved. Patient recruitment had not yet started at the time of manuscript submission. The study had not yet gained ethical approval at both the central and local levels at the time of manuscript submission. Central ethical approval has been confirmed from Peking University People’s Hospital (approval no. 2019PHA049-001), and we will not begin recruiting at other centers in the trial until local ethical approval has been obtained.
: Not applicable.
: The authors declare that they have no competing interests.