Funding for this research was provided by:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR107517)
Oregon Clinical and Translational Research Institute (UL1TR002369)
Received: 25 November 2019
Accepted: 6 February 2020
First Online: 4 March 2020
Ethics approval and consent to participate
: The study has been reviewed and approved by the Trial Innovation Network Single IRB at the University of Utah (IRB_00106351, initial approval February 7, 2018) for all participating sites with reliance from each regional IRB. The trial is registered at ExternalRef removed (ID: NCT03409367). Informed consent will be obtained from all study participants enrolled into the trial. Protocol amendments will be approved by the University of Utah and local IRBs, and shared with the Data and Safety Monitoring Board.
: Not applicable.
: The authors declare that they have no competing interests.