Funding for this research was provided by:
Key Science and Technology Program of Sichuan Province, China (2016FZ0118)
West China Hospital, Sichuan University (ZYGD18021, ZYJC18009, 2019HXFH060)
Received: 29 April 2020
Accepted: 7 February 2021
First Online: 1 March 2021
Ethics approval and consent to participate
: Ethical approval has been obtained from the Institutional Ethics Committee for Clinical Research of West China Hospital, Sichuan University (NO. 2018-289). Only participants who have provided informed consent in writing will be recruited.The protocol is made available in the Chinese CTR database. Important protocol modifications, such as changes to eligibility criteria or measured outcomes, will be reported to investigators and ethics committees before the change is implemented. If approved, the protocol changes will then be communicated to trial registries, journals, and external regulators.
: Not applicable.
: The authors declare they have no competing interests.