Funding for this research was provided by:
Received: 16 May 2021
Accepted: 15 December 2021
First Online: 27 December 2021
: The PORTAL trial has been approved by the Ruijin Hospital and Shanghai JiaoTong University School of Medicine Ethics Committee (Reference number KY2020-93) and has been designed and conducted according to the principles of the Helsinki Declaration (64th WMA General Assembly, October 2013). All eligible patients will sign an informed consent to participate in the trial prior to randomization. A copy of the consent form is available upon request.
: All eligible patients will declare consent for publication of de-identified data at the time of informed consent for enrollment in the PORTAL trial. A copy of the consent form is available upon request.
: The authors declare that they have no competing interests.